Dr. Rick Strassman's research on human DMT was sanctioned by the government. This research along with its various facets (the theories, challenges, trials and observations) find place in a documentary titled The Spirit Molecule, another name given to dimethyltryptamine (DMT) which is a endogenous psychoactive compound found in several plants and animals. The documentary traces the trials and tribulations in the research and is a detailed examination of the effects of the compound from the perspective of science and spirituality, two concepts which are apparently at war with each other. Is there a relation between the hi-tech developments in neuroscience, quantum physics and spirituality in humans A number of interesting questions are raised by the research of Strassman and the experiences of the human subjects after, during and before the intense trials. Contributors analyze these theories and experts come out with their experiences with DMT in their individual professions, each of which is unique in their own special way.